Sometimes
abnormal cells develop in the breast tissue, forming
a lump or tumor. This is the most common type
of cancer in women.
The
breast has several lobes, which are divided into
lobules and end in the milk glands. Tiny ducts
run from the many tiny glands, connect together,
and end in the nipple. Any tissue in the breast
can be affected and it will destroy the nearby
tissues also. Usually the cancer arises
from tissue that forms milk ducts. There are at
least 15 different kinds, depending on the
site of development . Both women and men
can develop breast cancer, but it is very rare
in men.
Breast cancer occurs more commonly in the left
breast than the right and more commonly in the
outer upper quadrant. The tumor may distort the
shape of the breast or the texture of the skin
as it becomes larger. It can be detected when
it grow large enough to either be felt or seen
on a mammogram.
The
cancer cells spread through the specialised channels
in the breast called lymphatics to the lymph nodes
to form tumors. It also spread or metasize to
the other parts of the body through the blood
stream. It spreads through the right side of the
heart to the lungs, and eventually to the other
breasts, the chest wall, liver, bone and brain.
Spreading of the tumor to other parts of the body
can cause death.
Breast
cancer can be classified by histologic appearance
and location of the lesion.
-
Adenocarcinoma
- arising from the epithelium.
-
Intraductal
- developing within the ducts
-
Infiltrating
- Occurring in parenchyma of the breast.
-
Inflammatory
- reflecting rapid tumor growth, in which
the overlying skin become edematous, inflamed
and in-durated.
-
Lobular
carcinoma in situ - reflecting tumor growth
involving lobes of glandular tissue.
-
Medullary
or circumscribed - large tumor with rapid
growth rate.