Definitions of Cancer.
(1). Any malignant growth
or tumor caused by abnormal and uncontrolled
cell division; it may spread to other parts
of the body through the lymphatic.
(2). Cancer (medical
term: malignant neoplasm) is a class of diseases
in which a group of cells display uncontrolled
growth (division beyond the normal limits),
invasion (intrusion on and destruction of
adjacent tissues), and sometimes metastasis
(spread to other locations in the body via
lymph.
Common types Of Cancer:
Bladder Cancer:
Definition of bladder cancer: Cancer that forms in tissues of the bladder (the
organ that stores urine). Most bladder cancers
are transitional cell carcinomas (cancer that
begins in cells that normally make up the
inner lining of the bladder). Other types
include squamous cell carcinoma (cancer that
begins in thin, flat cells) and adenocarcinoma
(cancer that begins in cells that make and
release mucus and other fluids). The cells
that form squamous cell carcinoma and adenocarcinoma
develop in the inner lining of the bladder
as a result of chronic irritation and inflammation.
Estimated new cases and deaths
from bladder cancer in the United States in
2009:Cases: 70,980.
Deaths: 41330
Common Causes
of Bladder Cancer:
● Smoking: Smoking is the single
greatest risk factor for bladder cancer. Smokers
have more than twice the risk of developing
bladder cancer as nonsmokers.
●Chemical exposures at work:
People who regularly work with certain chemicals
or in certain industries have a greater risk
of bladder cancer than the general population.
Organic chemicals called aromatic amines are
particularly linked with bladder cancer.
● Diet: People whose diets include
large amounts of fried meats and animal fats
are thought to be at higher risk of bladder
cancer.
Breast
Cancer :
Definition of breast cancer: Cancer that forms in tissues of the breast, usually
the ducts (tubes that carry milk to the nipple)
and lobules (glands that make milk). It occurs
in both men and women, although male breast
cancer is rare.
Estimated new cases and deaths
from breast cancer in the United States in
2009:cases: 192,370 (female); 1,910
(male)
Deaths: 40,170 (female); 440 (male)
Stages of Breast Cancer :
| Stage |
Definition |
| Stage 0 |
Cancer cells remain inside
the breast duct, without invasion into
normal adjacent breast tissue. |
| Stage I |
Cancer is 2 centimeters or
less and is confined to the breast (lymph
nodes are clear). |
| Stage IIA |
No tumor can be found in
the breast, but cancer cells are found
in the axillary lymph nodes (the lymph
nodes under the arm)
OR
the tumor measures 2 centimeters
or smaller and has spread to the axillary
lymph nodes OR
the tumor is larger than 2 but no
larger than 5 centimeters and has
not spread to the axillary lymph nodes. |
| Stage IIB |
The tumor is larger than
2 but no larger than 5 centimeters and
has spread to the axillary lymph nodes
OR
the tumor is larger than 5 centimeters
but has not spread to the axillary lymph
nodes. |
| Stage IIIA |
No tumor is found in the
breast. Cancer is found in axillary
lymph nodes that are sticking together
or to other structures, or cancer may
be found in lymph nodes near the breastbone
OR
the tumor is any size. Cancer has spread
to the axillary lymph nodes, which are
sticking together or to other structures,
or cancer may be found in lymph nodes
near the breastbone. |
| Stage IIIB |
The tumor may be any size
and has spread to the chest wall and/or
skin of the breast AND
may have spread to axillary lymph nodes
that are clumped together or sticking
to other structures, or cancer may have
spread to lymph nodes near the breastbone.
|
| Stage IIIC |
There may either be no sign
of cancer in the breast or a tumor may
be any size and may have spread to the
chest wall and/or the skin of the breast
AND
the cancer has spread to lymph nodes
either above or below the collarbone
AND
the cancer may have spread to axillary
lymph nodes or to lymph nodes near the
breastbone. |
| Stage IV |
The cancer has spread — or
metastasized — to other parts of the
body. |
Breast Cancer Statistics:
● Breast cancer incidence in women in the United
States is 1 in 8 (about 13%).
● In 2008, an estimated 182,460 new
cases of invasive breast cancer are expected
to be diagnosed in women in the U.S., along
with 67,770 new cases of non-invasive (in
situ) breast cancer.
● About 1,990 new cases of invasive
breast cancer will be diagnosed in men in
2008. Less than 1% of all new breast cancer
cases occur in men.
● From 2001 to 2004, breast cancer incidence
rates in the U.S. decreased by 3.5% per year.
One theory is that this decrease was due to
the reduced use of hormone replacement therapy
(HRT) by women after the results of a large
study, called the Women’s Health Initiative,
were published in 2002. These results suggested
a connection between HRT and increased breast
cancer risk.
● About 40,480 women in the U.S. are
expected to die in 2008 from breast cancer,
though death rates have been decreasing since
1990. These decreases are thought to be
the result of treatment advances, earlier
detection through screening,
and increased awareness.
Breast Cancer
Risk Factors:
By now you may be familiar
with the statistic that says 1 in 8 women
will develop breast cancer. Many people misinterpret
this to mean that, on any given day, they
and the women they know have a 1-in-8 risk
of developing the disease. That’s simply not
true.
In reality, about 1 in 8 women in the United
States — or 13%, or 13 out of every 100 —
can expect to develop breast cancer over the
course of an entire lifetime. In the U.S.,
an average lifetime is about 80 years. So,
it’s more accurate to say that 1 in 8 women
in the U.S. who reach the age of 80
can expect to develop breast cancer. In each
decade of life, the risk of getting breast
cancer is actually lower than 13% for most
women.
Diagnostics / symptom of Breast Cancer:
According to the American
Cancer Society, any of the following unusual
changes in the breast can be a symptom of
breast cancer:
swelling of all or part of the breast ,
● Skin irritation or dimpling
● Breast pain
●Nipple pain or the nipple turning inward
● Redness, scaliness, or thickening
of the nipple or breast skin
● A nipple discharge other than breast
milk
● A lump in the underarm area
Treatment for patients with cancer:
Different types of
treatment are available for patients with
breast cancer are,
(1). Surgery:
● Breast-conserving surgery, an
operation to remove the cancer but not the
breast itself, includes the following:
● Lumpectomy: Surgery to remove a tumor (lump) and a small amount
of normal tissue around it.
● Partial mastectomy: Surgery
to remove the part of the breast that has
cancer and some normal tissue around it. This
procedure is also called a segmental mastectomy.
Other types of surgery include
the following:
● Total mastectomy: Surgery
to remove the whole breast that has cancer.
This procedure is also called a simple mastectomy.
Some of the lymph nodes under the arm may
be removed for biopsy at the same time as
the breast surgery or after. This is done
through a separate incision.
● Modified radical mastectomy:
Surgery to remove the whole breast that has cancer,
many of the lymph nodes under the arm, the
lining over the chest muscles, and sometimes,
part of the chest wall muscles.
(2) .Radiation
therapy:
Radiation therapy is a cancer treatment that uses
high-energy x-rays or other types of radiation
to kill cancer cells or keep them from growing.
There are two types of radiation therapy.
External radiation therapy uses a machine
outside the body to send radiation toward
the cancer. Internal radiation therapy uses
a radioactive substance sealed in needles,
seeds, wires, or catheters that are placed
directly into or near the cancer. The way
the radiation therapy is given depends on
the type and stage of the cancer being treated.
(3). Chemotherapy:
Chemotherapy is a cancer treatment that uses drugs
to stop the growth of cancer cells, either
by killing the cells or by stopping them from
dividing. When chemotherapy is taken by mouth
or injected into a vein or muscle, the drugs
enter the bloodstream and can reach cancer
cells throughout the body (systemic chemotherapy).
When chemotherapy is placed directly into
the spinal column, an organ, or a body cavity
such as the abdomen, the drugs mainly affect
cancer cells in those areas (regional chemotherapy).
The way the chemotherapy is given depends
on the type and stage of the cancer being
treated.
(4). Hormone therapy:
Hormone therapy is a cancer treatment that removes
hormones or blocks their action and stops
cancer cells from growing. Hormones are substances
produced by glands in the body and circulated
in the bloodstream. Some hormones can cause
certain cancers to grow. If tests show that
the cancer cells have places where hormones
can attach (receptors), drugs, surgery, or
radiation therapy are used to reduce the production
of hormones or block them from working. The
hormone estrogen, which makes some breast
cancers grow, is made mainly by the ovaries.
Treatment to stop the ovaries from making
estrogen is called ovarian ablation.
(5). Targeted therapy:
Targeted therapy is
a treatment that targets faulty genes or proteins
that contribute to cancer growth and development.
Targeted therapy is usually given along with
another type of treatment, such as chemotherapy.
Because these drugs target specific genes
or proteins, a test may be needed to find
out if the drug will work for a specific type
of tumor. Although there aren’t a wide variety
of tests available now, many more may be available
in the future or as part of a clinical trial
as doctors seek to give patients the best
possible treatment for their type of cancer.
(6) .Immunotherapy:
Immunotherapy (also called
biologic therapy) is designed to boost the
body's natural defenses to fight the cancer.
It uses materials either made by the body
or in a laboratory to bolster, target, or
restore immune system function. Interferon
and colony-stimulating factor are two examples
of immunotherapy. The side effects of immunotherapy
generally include flu-like symptoms, such
as chills, nausea, and fever. Immunotherapy
also includes cancer vaccines—an investigational
approach to helping the immune system fight
cancer.
(7). Bone
marrow and stem cell transplantation:
Blood and marrow transplantation
is a medical (not a surgical) procedure, lasting
weeks to months from start to finish, in which
diseased marrow (a spongy, fatty tissue found
on the inside of larger bones) or immune system
is replaced by a healthier one. For people
with cancer, the goal is to destroy every
remaining cancer cell.
Precautions to Prevent Cancer.
Nearly half of
all cancer deaths are preventable.
That remarkable news
comes with an equally stunning corollary --
the key to success doesn't rest with some
undiscovered therapies or treatments. Much
of cancer's toll can be reduced with simple
precautions, such as lifestyle changes and
routine screenings.
But somehow that message isn't getting through
to enough people.
The biggest threat, of course, is smoking.
"You'd have to live on another planet not
to know smoking causes cancer," Aldige said.
Smoking is the single most preventable cause
of death in U.S. society. Tobacco causes nearly
one in five deaths in the United States, killing
about 438,000 Americans each year, according
to the American Cancer Society. Yet, about
45 million adults still smoke -- about 23
percent of men and 19 percent of women.
Need more proof that much of cancer's misery
is self-inflicted?
Experts estimate that about one in three of
the 564,830 deaths from all forms of cancer
this year will be related to poor nutrition,
inactivity, overweight and obesity.
Eventually, there will even be screenings
for lung cancer, probably in the form of "spiral
CT" scanning, using special equipment to obtain
multiple cross-sectional images of the organs
and tissues of the chest, Aldige said.
Then there's melanoma, the deadly skin cancer
that's on the rise. An estimated 62,190 new
cases of the disease will be diagnosed in
the United States this year, and 7,910 people
will die of it, according to the American
Cancer Society.
But melanoma is highly curable if it's caught
in its early stages. The best way to do that:
Check your own skin about once a month and
become familiar with the pattern of moles,
freckles, and other marks so you'll spot any
changes. And a skin exam should be part of
a routine cancer checkup by a doctor or qualified
health professional.