Diabetes.
What
is Diabetes.
Diabetes is a disorder
that affects the way your body uses food for energy.
Normally, the sugar you take in is digested and broken
down to a simple sugar, known as glucose. The glucose
then circulates in your blood where it waits to enter
cells to be used as fuel. Insulin, a hormone produced
by the pancreas, helps move the glucose into cells.
A healthy pancreas adjusts the amount of insulin based
on the level of glucose. But, if you have diabetes,
this process breaks down, and blood sugar levels become
too high.
Type
1 Diabetes:
A person with Type
1 diabetes can't make any insulin. Type 1 most often
occurs before age 30, but may strike at any age. Type
1 can be caused by a genetic disorder. The origins
of Type 1 are not fully understood, and there are
several theories. But all of the possible causes still
have the same end result: The pancreas produces very
little or no insulin anymore. Frequent insulin injections
are needed for Type 1.
Type
2 Diabetes:
A person with Type 2
diabetes has adequate insulin, but the cells have
become resistant to it. Type 2 usually occurs in adults
over 35 years old, but can affect anyone, including
children. The National Institutes of Health state
that 95 percent of all diabetes cases are Type 2.
Why? It's a lifestyle disease, triggered by obesity,
a lack of exercise, increased age and to some degree,
genetic predisposition.
Risk Factors For Type 2 Diabetes:
1.
Obesity:
The number one risk factor
for type 2 diabetes is obesity. The National Center
for Health Statistics states that 30% of adults are
obese. That's 60 million people. Greater weight means
a higher risk of insulin resistance, because fat interferes
with the body's ability to use insulin. According
to the same study, the number of overweight kids has
tripled since 1980. The number of children being diagnosed
with type 2 diabetes has also risen.
2.
Sedentary Lifestyle:
The Surgeon General's
Report on Physical Activity and Health (USA, 1996)
states that "a sedentary lifestyle is damaging to
health and bears responsibility for the growing obesity
problems." Inactivity and being overweight go hand
in hand towards a diagnosis of type 2. Muscle cells
have more insulin receptors than fat cells, so a person
can decrease insulin resistance by exercising. Being
more active also lowers blood sugar levels by helping
insulin to be more effective.
3.
Unhealthy Eating Habits:
Ninety% of people who
have been diagnosed with type 2 diabetes are overweight.
Unhealthy eating contributes largely to obesity. Too
much fat, not enough fiber, and too many simple carbohydrates
all contribute to a diagnosis of diabetes. Eating
right is can turn the diagnosis around and reverse
or prevent Type 2.
4.
Family History and Genetics:
It appears that people
who have family members who have been diagnosed with
type 2 diabetes are at a greater risk for developing
it themselves. African Americans, Hispanic-Americans
and Native Americans all have a higher than normal
rate of type 2 diabetes. Having a genetic disposition
towards type 2 is not a guarantee of a diagnosis however.
Lifestyle plays an important part in determining who
gets diabetes.
5.
Increased Age:
It's
a sad but true fact. The older we get, the greater
our risk of type 2 diabetes. Even if an elderly person
is thin, they still may be predisposed to getting
diabetes. Scientists theorize that the pancreas ages
right along with us, and doesn't pump insulin as efficiently
as it did when we were younger. Also, as our cells
age, they become more resistant to insulin as well.
6.
High Blood Pressure and High Cholesterol:
These two bad boys are
the hallmark risk factors for many diseases and conditions,
including type 2 diabetes. Not only do they damage
your heart vessels but they are two key components
in metabolic syndrome, a cluster of symptoms including
obesity, a high fat diet, and lack of exercise. Having
metabolic syndrome increases your risk of heart disease,
stroke, and diabetes.
Signs and Symptoms of Diabetes:
The common sign and symptoms of diabetes
are,
1. Frequent trips to the bathroom:
Are you visiting the
bathroom much more lately? Does it seem like you urinate
all day long? Urination becomes more frequent when
there is too much glucose in the blood. If insulin
is nonexistent or ineffective, the kidneys can't filter
glucose back to the blood. They become overwhelmed
and try to draw extra water out of the blood to dilute
the glucose. This keeps your bladder full and it keeps
you running to the bathroom.
Unquenchable
Thirst:
If it feels like
you can't get enough water and you're drinking much
more than usual, it could be a sign of diabetes, especially
if it seems to go hand in hand with frequent urination.
If your body is pulling extra water out of your blood
and you're running to the bathroom more, you will
become dehydrated and feel the need to drink more
to replace the water that you are losing.
Losing
Weight Without Trying:
This symptom is more
noticeable with Type 1 diabetes. In Type 1, the pancreas
stops making insulin, possibly due to a viral attack
on pancreas cells or because an autoimmune response
makes the body attack the insulin producing cells.
The body desperately looks for an energy source because
the cells aren't getting glucose. It starts to break
down muscle tissue and fat for energy. Type 2 happens
gradually with increasing insulin resistance so weight
loss is not as noticeable.
Weakness
and Fatigue:
It's that bad boy
glucose again. Glucose from the food we eat travels
into the bloodstream where insulin is supposed to
help it transition into the cells of our body. The
cells use it to produce the energy we need to live.
When the insulin isn't there or if the cells don't
react to it anymore, then the glucose stays outside
the cells in the bloodstream. The cells become energy
starved and you feel tired and run down.
Tingling
or Numbness in Your Hands, Legs or Feet:
This symptom is called
neuropathy. It occurs gradually over time as consistently
high glucose in the blood damages the nervous system,
particularly in the extremities. Type 2 diabetes is
a gradual onset, and people are often not aware that
they have it. Therefore, blood sugar might have been
high for more than a few years before a diagnosis
is made. Nerve damage can creep up without our knowledge.
Neuropathy can very often improve when tighter blood
glucose control is achieved.
After a Diabetes Diagnosis:
Having diabetes
is like being in charge of an octopus. There isn't
just one cut and dried way of coping with the disease
because of all of its different parts. At first, it
might seem like an overwhelming amount of information
is thrown at you. There are medications, food plans,
and schedules.
It
Doesn't Change Who You Are:
First of all, take
a deep breath. Realize you are still you, and that
over time, diabetes will become only one facet of
your life, and everything will eventually fit into
your lifestyle. It is possible to get a handle on
diabetes and live a long and healthy life.
Know
Your Blood Glucose Levels:
Check your blood
sugar several times a day. First thing in the morning,
before meals, after meals and before bed. Also anytime
when you feel like your blood sugar may not be "right".
● Keep records of all your blood glucose numbers
and what time you checked them.
● Keep a food diary of what you eat, how much
you eat and when you eat.
Records are good to keep because they tell you and
your doctor a lot about how you're doing, and whether
the medications or insulin schedule are at the best
dose for you.
Take
Your Medicine:
It's important to take your medications
as prescribed, even if you're feeling better. They
keep your blood sugar levels in a good range, so you
can reduce the risk of long-term complications like
nerve damage, blindness or kidney failure.
Plan
Your Meals:
● What to eat: a good balance of
carbohydrates, proteins and fats. The ADA has an exchange
list that might be helpful for determining what proportions
of carbs, proteins and fats you need.
● When to eat: Try to eat at the same times
everyday. This helps blood sugar levels remain constant.
● How much to eat: Use portion control to get
a balance of the nutrients that you need.
Get
Your Exercise:
Find an exercise that you like to do that
fits into your life.
● Exercise helps with weight loss.
● Exercise can increase the effectiveness of
insulin receptors in Type 2 diabetes.
● Exercise can lower immediate blood sugar in
both Type 1 and Type 2.
● Exercise can improve your mood.
Treatments for Diabetes:
Treatments
for Type 1 Diabetes:
Insulin Action Reference Chart:
There are many types of insulin, and they are
not all created equal. Each kind has its own unique
action, and they are not interchangeable. Which insulin
is right for you? The chart below will help you understand
how the various insulin medications work and why your
doctor has prescribed them for you.
There are three characteristics that define types
of insulin.
● Onset: How long it takes for the insulin to
start lowering blood glucose.
● Peak Time: Time after injection when the insulin
is the most effective at lowering blood glucose.
● Duration: How long the insulin keeps lowering
blood glucose.
Insulin is prescribed by matching the characteristics
of a particular insulin with the individual needs
of the patient. Some people are on only one kind of
insulin, while others take a combination of insulin
medication to customize good glucose control.
There are four main types of insulin available.
● Rapid acting
● Regular
● Intermediate acting
● Long acting
There are also pre-mixed insulins. These combine intermediate
acting insulins with regular insulin and are convenient
for people who need to use both.
Insulin Types and Actions:
| INSULIN
TYPES AND ACTIONS |
| Brand
Name |
Generic
Name |
Onset |
Peak |
Duration |
| RAPID
ACTING |
| Apidra |
Insulin
Glulisine |
<15
minutes |
1-2
hours |
3-4
hours |
| Humalog |
Insulin
Lispro |
<15
minutes |
1-2
hours |
3-4
hours |
| Novolog |
Insulin
Aspart |
<15
minutes |
1-2
hours |
3-4
hours |
| REGULAR |
| Humulin
R |
Regular |
1/2
- 1 hour |
2-3
hours |
3-6
hours |
| Novolin
R |
Regular |
1/2
- 1 hour |
2-3
hours |
3-6
hours |
| INTERMEDIATE
ACTING |
| Humulin
N |
NPH |
2-4
hours |
4-10
hours |
10-16
hours |
| Novolin
N |
NPH |
2-4
hours |
4-10
hours |
10-16
hours |
| LONG
ACTING |
| Levemir |
Insulin
Detemir |
3/4
- 2 hours |
minimal
peak action |
up
to 24 hours |
| Lantus |
Insulin
Glargine |
2-4
hours |
no
peak |
20-24
hours |
Oral Medication For type 2 Diabetes:
Main Categories
of Oral Medications:
1. Sulfonylureas:
These medications are the oldest of the
oral meds. Tolinase (tolazamide) has been around since
the 1950's. It's still prescribed today.
2.
Biguanides:
These drugs work by affecting the production
of glucose that comes from digestion. They don't cause
hypoglycemia and even help with weight loss and lower
cholesterol numbers.
3.
Alpha-Glucosidase Inhibitors:
Glyset (miglitol) and Precose (acarbose)
are the two most prescribed alpha-glucosidase inhibitors
(aka "starch blockers") They work differently than
the other medications reviewed so far. These medications
need to be taken at the beginning of each meal so
that they can work to slow digestion, which in turn
slows the rise of glucose in the blood.
4.
Thiazolidinediones :
These drugs work by sensitizing muscle
and fat cells to accept insulin more readily. Actos
(pioglitazone) and Avandia (rosiglitazone) are the
only two thiazolidinediones marketed today.
5.
Meglitinides:
This class of drugs is similar to the alpha-glucosidase
inhibitors in that they are taken before each meal.
But these drugs stimulate the pancreas to produce
more insulin in relationship to how much glucose is
in the blood.